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PRObiom® Dental – dental probiotic

Thank you for your interest in PRObiom® Dental. Here you will find professional information and materials to download. For healthy teeth and healthy gums.

PRObiom® Dental

Dental cosmetic

Oral and dental care product

Bacterial strain
Streptococcus salivarius M18 – on average at least 0.8 billion CFU per tablet at the end of the best-before date after 24 months. Proven efficacy from 0.5 billion CFU per tablet.
Pack size
30 lozenges (3 blisters of 10 lozenges each)
Content
24.3 g (30 tablets of 810 mg each)

Ingredients

Active ingredients

Streptococcus salivarius M18
is a natural, beneficial strain of a healthy oral microbiome. It displaces undesirable germs that are responsible, for example, for tooth decay and periodontal disease, thereby supporting the bacterial balance in the mouth. At the end of the best-before date, each PRObiom® Dental lozenge still demonstrably contains an effective amount of active Streptococcus salivarius M18 bacteria.
Natural peppermint flavour
in accordance with the EU Flavourings Regulation, ensures fresh breath.

Excipients

Isomalt
a tooth-friendly sugar substitute of no interest to bacteria in the oral cavity. Isomalt tastes similar to sugar but has only half the sweetening power.
Maltodextrin
a carbohydrate mixture obtained from starch. It serves as a carrier for the volatile peppermint flavour. Due to the small amount used, it is gentle on the teeth.
Trehalose
a natural double sugar (disaccharide) that helps the probiotic bacteria survive the dryness in the tablet.
Magnesium stearate
prevents the material from sticking in the tablet press.
Lactitol
a tooth-friendly sugar substitute.
Gum arabic
a natural, long-chain carbohydrate from the plant sap of the Verek acacia native to Africa. The resinous substance stabilises the peppermint flavour it contains.

Facts

  • With Streptococcus salivarius M18, PRObiom® Dental contains the world's most thoroughly studied probiotic bacterial strain for oral and dental health. [1]
  • Streptococcus salivarius M18 colonises the oral cavity effectively. [2]
  • Acts antibacterially through the production of unique antimicrobial substances (e.g. Salivaricin M) that inhibit the most important pathogens in the mouth and dental area (e.g. Streptococcus mutans, Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans). [1, 3]
  • Reduces pocket depth and supports the regeneration and recovery of the gums. [9]
  • Breaks down plaque through enzymatic activity (dextranase) and neutralises acidity (urease). [4]
  • Reduces pro-inflammatory cytokines (IL-6 and IL-8). [7]
  • Reduces plaque and key pathogens that cause tooth decay in children and tooth decay and periodontitis in adults. [5, 6, 8, 9]
  • High compliance thanks to good taste and single daily dose.
  • For all adults and children from 3 years of age.

References

  1. 1 Wescombe et al., Future Microbiol (2012)
  2. 2 Burton et al., PLoS (2013)
  3. 3 Internal Report (2016a)
  4. 4 Heng et al., J Bacteriol (2011)
  5. 5 Burton et al., J Med Microbiol (2013)
  6. 6 Di Pierro et al., Clin Cosmet Investig Dent (2015)
  7. 7 Adam et al., IADR/AADR/CADR 89th General Session and Exhibition (2011)
  8. 8 Internal Report (2016b)
  9. 9 Scariya et al., Int J Pharm Bio Sci (2015)

Downloads

Materials and studies to download.